Licocoumarone isolated from Glycyrrhiza uralensis selectively alters LPS-induced inflammatory responses in RAW 264.7 macrophages
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چکیده
منابع مشابه
Antibacterial compounds from Glycyrrhiza uralensis.
From the roots of Glycyrrhiza uralensis, two new pterocarpenes, glycyrrhizol A (1) and glycyrrhizol B (2), along with four known isoflavonoids, 5-O-methylglycryol (3), isoglycyrol (4), 6,8-diisoprenyl-5,7,4'-trihydroxyisoflavone (5), and gancaonin G (6), were isolated using a bioassay-guided fractionation method. The structures of the new compounds (1and 2) were elucidated by spectroscopic data...
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The present study was designed to investigate the inhibitory effect of 2,4 bis-[(4-ethoxyphenyl)azo] 5-(3-hydroxybenzylidene) thiazolidine-2,4-dione (TZD-OCH2CH3) on the cyclo-oxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) in RAW 264.7 cells. The effects of TZD-OCH2CH3 on COX-2 and iNOS mRNA expression in LPS-activated RAW 264.7 cells ...
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The present study was designed to investigate the inhibitory effect of 2,4 bis-[(4-ethoxyphenyl)azo] 5-(3-hydroxybenzylidene) thiazolidine-2,4-dione (TZD-OCH2CH3) on the cyclo-oxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) in RAW 264.7 cells. The effects of TZD-OCH2CH3 on COX-2 and iNOS mRNA expression in LPS-activated RAW 264.7 cells ...
متن کاملAldose reductase inhibitory compounds from Glycyrrhiza uralensis.
We evaluated the inhibitory effects of components from the root of Glycyrrhiza uralensis (G. uralensis) on aldose reductase (AR) and sorbitol formation in rat lenses with high levels of glucose as part of our ongoing search of natural sources for therapeutic and preventive agents for diabetic complications. In order to identify the bioactive components of G. uralensis, 5 prenylated flavonoids (...
متن کاملChemical profile and anti-inflammatory activity of total flavonoids from Glycyrrhiza uralensis Fisch.
Glycyrrhiza uralensis Fisch. (G. uralensis) is one of the most widely used herbal medicines for the treatment of cough, spasms, pain, inflammation and low immunity This study was designed to enrich total flavonoids (TFF) from G. uralensis and investigate the anti-inflammatory activity of TFF. The anti-inflammatory activity was evaluated by inflammatory models of dimethylbenzene (DMB)-induced ea...
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ژورنال
عنوان ژورنال: European Journal of Pharmacology
سال: 2017
ISSN: 0014-2999
DOI: 10.1016/j.ejphar.2017.02.049